Similarly, MM-MSC-derived exosomes were found to contain cytokines including monocyte chemotactic protein 1 (MCP-1), interferon-inducible protein 10 (IP-10), and SDF-1, and were demonstrated to induce myeloma 5T33MM cell migration in vitro and home to the BM in vivo [106]. This evidence concerns the gene CCL2 and plasma cell myeloma.