NFE2L2 and colonic neoplasm: In addition, EGCG intake (5, 10, 20 mg/kg) for 4 weeks in BalB/cA nude mice injected with colon cancer HT-29 cells upregulated Nrf2 protein and mRNA levels and UGT genes such as UGT1A, UGT1A8, and UGT1A10.