Resveratrol can also attenuate the phosphorylation of the mammalian target of rapamycin (mTOR) and S6 ribosomal protein (S6RP) while ameliorating inflammation [455]. Several cellular and animal studies show that SIRT1 is neuroprotective in neuroinflammation and neurodegenerative diseases. The gene discussed is MTOR; the disease is neurodegenerative disease.