CRISPR/Cas9-based screens to identify essential genes for survival and proliferation of cancer cell lines analyzed via the depmap portal (www.depmap.org; Accessed on 26 March 2021) corroborates a fundamental function of MEX3A in tumor cell survival (Figure 2e) and suggests MEX3A as a common essential gene in liver cancer cell lines as well as in cell lines from different cancer origins. The gene discussed is MEX3A; the disease is neoplasm.