TNFSF11 and colonic neoplasm: A previous in vitro study also revealed that onion peel extract inhibits the lipopolysaccharide (LPS)-induced response in human colon cancer cells [16], and crude onion powder inhibits the receptor activator of nuclear factor kappa-B ligand (RANKL)-induced nuclear factor kappa-B (NF-κB) activation in RAW264.7 cells [17].