A previous study showed a confirmed association between HLA-B*15:02 and phenytoin-induced SJS/TEN in Malay patients (61.5% (8/13 cases) vs. 21.9% (7/32 controls), OR 5.71; p = 0.016) and showed a significant association between HLA-B*15:13 and both phenytoin-induced SJS/TEN (53.8% (7/13 cases), OR 11.28; p = 0.003) and phenytoin-induced DRESS (100% (3/3 cases), OR 59.00; p = 0.003) [71]. This evidence concerns the gene HLA-B and toxic epidermal necrolysis.