In this connection, 24-OHC has been shown to elicit a strong pro-inflammatory response in human neuroblastoma SH-SY5Y cells by inducing the expression of some pro-inflammatory mediators, including the chemokines interleukin 8 (IL-8) and monocyte chemotactic protein 1 (MCP-1), the adhesion molecule β1-integrin, the scavenger receptor CD36 and the matrix metalloproteinase 9 (MMP-9). This evidence concerns the gene MMP9 and neuroblastoma.