In line with these findings, a study in 40 patients, including 18 patients with a BRCA1-mutated tumor (n = 9) or a tumor with epigenetic loss of BRCA1 (n = 9), demonstrated that intraepithelial CD8+ TILs were more frequently observed in tumors with BRCA1 abnormalities (94.4% vs. 57.9%) [56]. The gene discussed is CD8A; the disease is neoplasm.