HAMP and obesity due to melanocortin 4 receptor deficiency: In a study of 245 pregnant women living with obesity and 245 normal-weight pregnant women, Flynn et al. [86] reported significantly elevated CRP and IL-6 levels in obese vs. lean pregnant women, with no difference in serum ferritin or serum hepcidin levels at 15–18 weeks gestation, suggesting that at least at this stage of pregnancy maternal hepcidin is not driven by inflammation.