Further, fabp10 promoter-driven transgenics analyzed with RNA-seq using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes databases have shown that Xmrk-induced zebrafish HCC gene expression is similar to human HCC subtype, S2, which is characterized by enhanced Myc signaling, phosphorylated-ribosomal protein, S6, and epithelial cell adhesion molecule regulation [19] (Figure 2). This evidence concerns the gene MYC and hepatocellular carcinoma.