Upregulation of miR-182 promotes migration and survival in human melanoma cell lines by preventing the transcription factors, MITF-M and FOXO3, and downregulates Bcl-2, cyclin D2, c-Met, the Akt and ERK1/2 pathways while increasing β-catenin expression [120,121,122] (Figure 1). This evidence concerns the gene MAPK3 and melanoma.