We also demonstrated that in mesenchymal stromal cells (MSC) from Hodgkin lymphoma (HL), ADAM10 binds to specific fluorescent inhibitors targeting its active site, colocalizing with Rab5-positive early endosomes and with LysoTrackerRed in endolysosomal vesicles [105]. The gene discussed is RAB5A; the disease is Hodgkins lymphoma.