IL1B and neoplasm: When we used CM from IL1β-stimulated NCF (48 h of fibroblast stimulation), IL1β targets secreted into the culture medium from NCFs enhanced the migratory capabilities of tumor cells to an almost statistically significant extent relative to control or NCF CM (Kruskal–Wallis test, with Dunn’s post hoc multiple comparison test, adjusted p = 0.051; Figure 2G).