BCAS1 and multiple system atrophy: Moreover, in vitro aSyn overexpression in oligodendrocytes resulted in delayed maturation of oligodendrocyte progenitor cells and impaired myelin-gene expression and myelination deficits [679,680,681], whereas in another study aSyn-positive inclusions were mainly detected in BCAS1-expressing (breast carcinoma amplified sequence 1) immature oligodendrocytes of MSA brains [682].