INS and hydrops fetalis: Our real-world study found that in patients with HF and T2D with poor glycemic control, switching from non-metformin oral antidiabetic agents to canagliflozin simplified treatment led to reductions in the number of antidiabetic agents, basal insulin doses, and percentage of patients who use diuretics and led to improved glycemic control, with reductions in BG and HbA1c levels.