Otherwise, the activation of the transcription factor SREPB (sterol regulatory element binding protein) signalling pathway was required in the poor survival glioblastoma multiforme to preserve lipid biosynthesis and cell viability under lipid- and O2-deprived conditions [84], which was herein in agreement with the upregulated expression of fdps and mvd in both N-PF and M-HYP fish. The gene discussed is FDPS; the disease is glioblastoma.