CRP and Decreased total leukocyte count: Paraclinical data show leukopenia, lymphopenia, thrombocytopenia, hypoalbuminemia, alarming increase in C-reactive protein (CRP), serum ferritin, aminotransferase, lactate dehydrogenase (LDH), D-dimer and decreased alkaline reserve, and so on, implying a particularly severe immunopathology.