PBM stabilize the function of the immune system (drop the level of pro-inflammatory cytokines such as IL-1β, IL-6, IL-8, TNFα, and MCP-1 and improve the balance of IL-10) in severe COVID-19 cases, decreasing the impact of cytokine storm as the main cause of high mortality in ARDS patients [300]. Here, IL6 is linked to acute respiratory distress syndrome.