GLI1 and medulloblastoma: The excessive synthesis of proteins encoded by Gli1 and Gli2, which are elements of the Hedgehog pathway, results in the development of SHH medulloblastoma overexpression of the downstream genes affecting the cell proliferation (CCND1, CCND2, CCNE, MDM2), stem cell regeneration (GREM1), cell survival (BCL2, CFLAR), and angiogenesis (VEGF) [136,137,138].