CYP19A1 and breast cancer: One study compared 102 premenopausal and 59 postmenopausal women who underwent mastectomy for breast cancer treatment or prevention and found that postmenopausal women were more likely to have a higher BMI, larger breast adipocytes, severe breast WAT inflammation as measured by the number of CLS-B/cm2, and greater local aromatase activity than premenopausal women [72].