DEPTOR and Miyoshi myopathy: c-Maf, in particular, promotes MM cell proliferation via cyclin D2; cell migration and invasion via ARK5; cell survival via DEP domain-containing mTOR-interacting protein (DEPTOR)-dependent activation of the PI3K/AKT pathway; and pathological interactions between BM stroma and MM cells followed by VEGF secretion via integrin β7 [34,35,36,37,57].