Recently, miRNA-29 family (miR-29a/b/c) was proven as proliferation, invasion and migration suppressors for gliomas by targeting cell division cycle 42 (CDC42) [32] and Sterol regulatory element binding protein 1 (SREBP-1)/SREBP cleavage-activating protein (SCAP) in animal models [83]. The gene discussed is CDC42; the disease is central nervous system cancer.