H2AX and neoplasm: In contrast, functions show a negative impact on “Cell death of tumor cell lines” (z-score = −3.96, p = 1.22 × 10−18), “Necrosis” (z-score = −4.61, p = 3.78 × 10−13), “Formation of gamma H2AX nuclear focus” (z-score = −2.62, p = 5.39 × 10−8), “Quantity of microtubules” (z-score = −2, p = 7.48 × 10−6) and “Formation of mitotic spindle” (z-score = −1.46, p = 1.20 × 10−16) (Figure 5A).