The TCGA data showed that the mRNA levels of TRIP13 increased in response to radiation (n = 417), compared to those without radiotherapy (n = 209) for LGG samples (Figure 3A) (no statistically significant difference in GBM), suggesting that radiosensitive role for TRIP13 may be different on grades of glioma. The gene discussed is TRIP13; the disease is central nervous system cancer.