Plasma C3 complement levels were significantly correlated with LDL-C levels (Spearman correlation: Rho value = 0.412, p < 0.001), ApoB levels (Spearman correlation: Rho = 0.562, p < 0.001) and Lp(a) (Spearman correlation: Rho = 0.244, p = 0.034) when the whole study population was considered (healthy subjects and FH patients) (Figure 1B). The gene discussed is APOB; the disease is familial hyperaldosteronism.