Figure 1B shows the distribution of PD-L1 scoring results in PD-L1 positive subsets of the algorithms. While IC5%, ICarea25% and TCarea25% positive tumors were enriched with PD-L1 positive IC or TC, CPS10 positive tumors represented a mixed continuum of tumors enriched with PD-L1 positive IC and TC (Figure 1B). In summary, current PD-L1 scoring algorithms identify very different tumor subsets with either predominant PD-L1 expression on IC (Ventana IC5%), TC (CPS10), or both (TCarea25%/ICarea25%). This evidence concerns the gene CD274 and neoplasm.