MFN2 and endometrial cancer: Moreover, SHetA2 significantly decreased levels of mitochondrial proteins involved in fusion, namely long form of outcome predictor in acute leukemia 1 (OPA1L), mitofusion 1 (MFN1), mitofusion2 (MFN2), and fission, namely, phosphorylated dynamin-related protein 1 (pDrp1) in the endometrial cancer cell lines (Figure 3B).