MET and non-small cell lung carcinoma: The ATP-competitive c-MET/ALK inhibitor crizotinib [203], followed by highly selective ATP-competitive c-MET inhibitors capmatinib [202] and tepotinib [201] have been successively approved by the United States Food and Drug Administration (US FDA) for the treatment of NSCLC in patients with MET exon 14 skipping alterations.