PNPLA3 and obesity due to melanocortin 4 receptor deficiency: Therefore, with a specific focus on Hispanic adolescents with obesity, this current cross-sectional study aims to: (1) identify potential biological predictors of liver fibrosis (i.e., liver fat, sex, PNPLA3 polymorphisms, and diet); and (2) determine if associations between dietary components and liver fibrosis differs by PNPLA3 genotype.