Similar results were also observed in a study by Giatromanolaki et al., who reported strong expression of PHD1, PHD2 and PHD3 proteins in normal bronchial epithelium and glands, whereas less than 50% of NSCLC cases were strongly positive for PHD 1, PHD2 and PHD3 [21]. The gene discussed is EGLN3; the disease is non-small cell lung carcinoma.