Multivariate Cox proportional hazards regression analysis adjusting for PS, pTNM stage, tumour size and nodular involvement revealed that lower PHD1 mRNA expression in the primary tumour had borderline significance for shorter OS (HR = 0.908; 95% CI: 0.822–1.004; p = 0.06) (Table 4). The gene discussed is EGLN2; the disease is neoplasm.