Next, we further investigated whether BMAL1-KD could influence the expression of cell adhesion molecules, such as integrin β1 (CD29), integrin alpha5 (CD49e), and CD44, that were involved in the matrix–cell adhesion [31,32] and the apico-basolateral polarity [33] of CRC cells (Figure 6). Here, ITGA5 is linked to colorectal carcinoma.