Based on the results of our comprehensive and comparative study, we demonstrated that the expression pattern of proteins such as Ras, ShcA (p66Shc, p52Shc, p46Shc) in astrocytic, oligodendrioglial, ependymal, choroid plexus, and embryonal tumors in children seem to be closely similar. This evidence concerns the gene SHC1 and embryonal neoplasm.