Two Phase I clinical trials conducted in Hong Kong [55] and the United Kingdom [56] with MVA-EL vaccinia vaccine encoding the full-length LMP2 and CD4+ T-Cell epitopes of EBNA1 with EBV-positive nasopharyngeal carcinoma patients reported that 23 out of 32 patients developed LMP2/EBNA1 specific CD8+ and CD4+ T-cell immunity (Hui et al., eight in 14 patients; Taylor et al., 15 in 18 patients). The gene discussed is CD4; the disease is nasopharyngeal carcinoma.