MAGEA3 and non-small cell lung carcinoma: MAGRIT multicentre trials recruited a total of 2312 completely resected stage IB, II, and IIIA MAGE-A3+ NSCLC patients to test the clinical efficacy of the recombinant MAGE-A3 protein (recMAGE-A3) supplemented with an AS15 immunostimulant (3-O-desacyl-4′-monophosphoryl lipid A (monophosphoryl lipid A; MPL), QS-21 (extract from the soap bark tree [Quillaja saponaria]) + a synthetic oligodeoxynucleotide containing unmethylated CG dinucleotides (CpG ODNs 7909), in a liposomal formulation) [39].