A similar observation was reported by Bao et al. since their study indicated that infection with the 2009 swine-original influenza A (H1N1) subtype (H1N1pdm09) induced Gal-1 expression in both A549 cells and mouse bronchoalveolar lavage fluid (BALF), and expression of Gal-1 ameliorated H1N1pdm09-induced acute lung injury [25]. This evidence concerns the gene LGALS1 and infection.