A copious amount of literature links basic leucine zipper transcription factors, ATF5, CEBPB and CEBPD, to tumor formation, growth, metastasis and treatment resistance in a variety of cancers [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29]. The gene discussed is CEBPB; the disease is cancer.