GPT and HIV-1 infection: Similarly, GS-US-236-0102 compared elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate versus efavirenz/emtricitabine/tenofovir disoproxil fumarate for initial treatment of HIV-1 infection; elevations in transaminases were more frequent in the efavirenz group: ALT (18% vs. 31%, respectively) and AST (15% vs. 35%, respectively) [49].