BRCA2 and cancer: In the cancer HotSpots Database, six BRCA2 mutations were identified at positions 1393, 1689, 1782, 2842, 3308, and 3342 (http://bioinformatica.mty.itesm.mx:8080/HotSpotsAnnotations/PiquinSpot.jsp?gene=BRCA2, accessed on 25 April 2021) [72].