In multivariate analyses for OS, AFP > 400 ng/mL (hazard ratio (HR), 2.07; 95% CI, 1.28–3.36; p < 0.05) and HCC of BM (HR, 2.61; 95% CI, 1.60–4.26; p < 0.05) were independent risk factors for OS among the preoperative characteristics. This evidence concerns the gene AFP and hepatocellular carcinoma.