Among both cohorts, there were individuals with mutations in RMS-associated cancer predisposition genes, including TP53, DICER1, NF1, MSH2, and MSH6. This study reported one individual with a heterozygous germline mutation in BRCA2 and another with biallelic germline mutations in BRCA2 consistent with Fanconi anemia D2. The gene discussed is DICER1; the disease is cancer.