We found, in our study, that 6 weeks of antipsychotic treatment led to an increase in some proinflammatory cytokines such as the IFN-α2, IL-1α and IL-7 levels in patients with MetS and to decreased IFN-γ, IL-1β, IL-12р40, IL-6 and TNF-α in patients without MetS. This evidence concerns the gene IL6 and metabolic syndrome.