In an attempt to identify noninvasive markers of liver fibrosis during chronic hepatitis C, the Enhanced Liver Fibrosis (ELF) test was put forward; it evaluates the serum levels of TIMP1, HA, and N-terminal peptide of procollagen type III (PIIINP) and includes age for statistical robustness [128]. The gene discussed is TIMP1; the disease is Hepatic fibrosis.