IFNG and neoplasm: We found that both the intracellular expression of IFNγ (Figure 6H, Kruskal–Wallis test, KW = 15.22, p = 0.002) and the mean fluorescent intensity of IFNγ (Figure 6I, Kruskal–Wallis test, KW = 6.88, p = 0.030) in stimulated CD44+CD8+ TILs were significantly increased in therapy-treated OB-RES mice relative to OB-RES NT mice at day 21 post-tumor challenge.