FN1 and lung adenocarcinoma: Reportedly, GT1b downregulates the expression of α5β1 integrin, caveolin-1, fibronectin, FAK, and ERK, while GT1b upregulates the expression of p53 and uPAR, resulting in downregulation of fibronectin-α5β1-integrin-ERK signaling in the A549 lung adenocarcinoma cell line.