When comparing the expression of ligands for inhibitory NK cell receptors with that of their normal counterpart cells (Figure 2B), leukemic blast cells showed higher expression of total HLA-I in B-ALL (38,277 ± 3708 vs. 45,314 ± 4975 MFI, n.s.)and AML (37,187 ± 9152 vs. 51,888 ± 9623 MFI, n.s.)but lower in T-ALL (37,122 ± 7468 vs. 17,559 ± 4387 MFI, p = 0.046); and lower expression of HLA-C in B-ALL (14,320 ± 1489 vs. 10,474 ± 1212 MFI, p = 0.028) and T-ALL (12,412 ± 2509 vs. 6861 ± 1832 MFI, p = 0.019) but similar levels in AML (7828 ± 1453 vs. 8877 ± 1523 MFI, n.s.). Here, HLA-C is linked to acute myeloid leukemia.