However, when studying patients individually, we detected lower expression (loss of HLA) on leukemic blasts compared to their normal counterpart cells for HLA-I in 42.4%, 93.3%, and 25.0% (p = 0.0002) and HLA-C in 75.8%, 86.7%, and 62.5% (p = 0.292) of B-ALL, T-ALL, and AML patients, respectively (Figure 3A). Here, HLA-C is linked to acute lymphoblastic leukemia.