CCND1 and neoplasm: Figure 3E shows the CNA genetic landscape of the residual tumor of four patients in group 1 who developed metastases. In addition to the presence of two or more amplifications of the stemness genes in each tumor, all patients had an amplification of the CCND1 gene. However, this amplification of the CCND1 gene were also observed in some other patients in this group who did not metastasize.