We found that the sensitivity was 1.0 and the specificity was 0.56 for the subjects who had reversibility of airway obstruction by 12-week-inhalation therapy of fluticasone propionate (FP)/Salmeterol (SAL) when FeNO > 35 parts per billion (ppb) and/or a positive result for specific IgE (atopy+) were combined [78]. Here, IGHE is linked to Airway obstruction.