In addition, our results show strong evidence for multiple association signals: one at chromosome 17p13.2 in HASPIN substantiating the importance of this gene in PD risk, and one at chromosome 4q22.1 in SNCA. SNPs at chromosome 4p22.1 are well known for their association with PD [15,32,33,34] and several other diseases including dementia with Lewy bodies [35]. This evidence concerns the gene HASPIN and Parkinson disease.