BRAF and melanoma: Despite the current available therapies and the progress recorded in melanoma treatment and diagnostic tools (targeted therapies for BRAF-mutated melanomas—vemurafenib, dabrafenib; immunotherapy—ipilimumab, nivolumab, pembrolizumab; and combined therapies), invasive melanoma remains the primary cause of skin cancer deaths and a continuous increment of melanoma incidence was recorded worldwide, even though the mortality rates decreased in the latest years [5].