In the SCAN-B cohort, high BIRC5 levels associated with significantly lower 5-year survival prognosis (ER-, HR 1.95 [1.06–3.31], p = 0.035; ER+, HR 1.63 [1.30–2.04], p < 0.0001). The gene discussed is BIRC5; the disease is spinocerebellar ataxia, autosomal recessive, with axonal neuropathy.