Concordantly, in multivariate Cox regression analyses (adjusted for tumor grade (G), tumor stage (T) and lymph node stage (N) of the tumor), lower serum GP88 levels were significantly associated with a 4.2-fold increased risk of death in the patient cohort (95% CI: 1.4–12.0; p = 0.008; see Figure 5; see also Table S1 and Figure S1). Here, GRN is linked to neoplasm.