NPM1 and acute myeloid leukemia: Of the commonly mutated genes in NK-AML, CEBPA/GATA2, FLT3/WT1, and FLT3/NPM1 were identified as frequently co-occurring events meanwhile mutated CEBPA was mutually exclusive of mutated NPM1 and FLT3. This is of importance to consider when investigating the clinical implications of mutations in these genes.