Of the most commonly mutated genes in NK-AML, we identified mutated CEBPA/GATA2 (p = 1.3 × 10−7), FLT3/WT1 (p = 0.03), and FLT3/NPM1 (p = 0.045) as commonly co-occurring events, whereas mutated CEBPA was likely to be mutually exclusive of both mutated NPM1 (p = 3.0 × 10−7) and FLT3 (p = 2.9 × 10−5). The gene discussed is FLT3; the disease is acute myeloid leukemia.