Notable tools for this are transient elastography, and serum biomarkers for cirrhosis or HCC such as ALT, AST, and α-fetoprotein, often in combination with risk formulas such as calculation of the AST to platelet ratio index (APRI) or the Fibrosis-4 index (FIB-4) [16,17]. Here, GPT is linked to hepatocellular carcinoma.