IL6 and Patent ductus arteriosus: In PDA cells alone at 24 h, an increase of VEGF and a decrease of MCP1 was measured (Figure 4a), while at 96 h, a decrease of CCL4, CXCL1, IL6, MCP1, TGFβ, and VEGF was found, with no target being investigated showing an increase with plasma exposure at this incubation time.