AKR1B10 and esophageal squamous cell carcinoma: Since high expression of AKR1B10 has been observed in an esophageal squamous cell carcinoma cell line, OE-21 [132], it would be interesting to analyze the expression of AKR1B10 in specimens from patients with squamous cell carcinoma, which is the predominant form of esophageal carcinoma worldwide.